The use of Proton Pump Inhibitors (PPIs) to treat acid reflux has been associated with serious side effects as the prevalence of this condition increases due to obesity and sedentary lifestyles. This has led to debates on whether surgery could be a more effective solution.
A recent study conducted by six U.S. universities analyzed data from over 5,700 individuals and found that prolonged use of PPI drugs for more than 4.4 years increased the incidence of dementia in individuals over 45.
Chris Sutton, clinical director of upper gastrointestinal surgery at Leicester Royal Infirmary, explains that PPIs are believed to interfere with beta-amyloid, a protein associated with dementia.
Acid reflux pills linked to side-effects… but is surgery the answer? https://t.co/1c4wKatNBt via @MailOnline
— greysunshelbyryanconroy (@ghwbjfkmlkrfk) September 18, 2023
Furthermore, PPIs have been associated with reduced absorption of vitamins and minerals from the diet, which may increase the risk of osteoporosis. They also promote the growth of harmful bacteria in the digestive system, which would normally be eliminated by stomach acid. Despite these concerns, some experts argue that the benefits of PPIs outweigh the potential harm.
However, as the number of people suffering from acid reflux continues to rise, there is a growing demand for surgical interventions. Bradley Phelps, a retired gardener from Leicester, underwent a new surgical approach using a device called RefluxStop. This procedure involves creating a small pouch at the junction of the esophagus and stomach and inserting a ceramic ball as a one-way valve. This innovative procedure allowed Bradley to return to a normal diet within a week of the operation.
Doctors ignore and misdiagnose women. I was given pills for anxiety when I actually had acid reflux. The pills caused severe emotional side effects. On my own I discovered what foods I could not eat and problem solved. Ignored symptoms and misdiagnosis made me anxious.
— May 🌻🇺🇦 (@clarnt) May 4, 2023
However, not all medical professionals are convinced about the effectiveness of this new approach. Professor Underwood from Southampton University argues that there is insufficient data on the success of RefluxStop and recommends it be used within a clinical trial setting.
While PPIs have been a common treatment for acid reflux, their long-term use has been linked to serious side effects. As the prevalence of acid reflux continues to rise, surgical interventions like the RefluxStop procedure may offer a promising alternative. However, more research is needed to validate the effectiveness and safety of these surgical procedures. Until then, patients and healthcare providers must carefully consider the benefits and risks of each treatment option.
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